发明名称 |
METHOD FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF BREAST CANCER METASTASIS |
摘要 |
The present invention relates to a method for the diagnosis or the prognosis of metastasis in breast cancer which comprises determining if the c-MAF gene is amplified in a primary tumor sample. Likewise, the invention also relates to a method for the diagnosis or the prognosis of metastasis in ER- breast cancer, as well as to a method for determining the tendency to develop bone metastasis with respect to metastasis in other organs, which comprise determining the c-MAF gene expression level. Finally, the invention relates to the use of a c-MAF inhibitor as therapeutic target for treating the ER- breast cancer metastasis. |
申请公布号 |
EP3091085(A1) |
申请公布日期 |
2016.11.09 |
申请号 |
EP20150180897 |
申请日期 |
2011.10.05 |
申请人 |
INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS;FUNDACIÓ INSTITUT DE RECERCA BIOMÈDICA (IRB BARCELONA) |
发明人 |
GOMIS CABRÉ, ROGER;ARNAL ESTAPÉ, ANNA;PAVLOVIC, MILICA;TARRAGONA SUNYER, MARIA |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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