发明名称 |
TRIAZINES AS PROTEIN BINDING LIGANDS |
摘要 |
<p>Compounds of the general formula (I): in which inter alia Q1 represents -NR1R3, -OR1 or -SR1 and Q2 represents -NR2R4, -OR2 or -SR2, and A represents the point of attachment to a support matrix, are useful as protein binding ligands when (a) at least one of R1, R2, R3 and R4 includes an alkyl group -CnH2n+1 in which n is greater than or equal to 7; (b) at least two of R1, R2, R3 and R4 independently include an alkyl group -CnH2n+1 or a cycloalkyl group -CnH2n-1 in which n is greater than or equal to 4; or (c) at least three of R1, R2, R3 and R4 independently include a C1-12 alkyl group substituted by -NR5R6 or aryl.</p> |
申请公布号 |
EP1899308(A2) |
申请公布日期 |
2008.03.19 |
申请号 |
EP20060744347 |
申请日期 |
2006.06.08 |
申请人 |
PROMETIC BIOSCIENCES LIMITED |
发明人 |
BETLEY, JASON, RICHARD;PEARSON, JAMES, CHRISTOPHER;TATTON, HELEN, ROSEMARY;BEACOM, BEN, MARTIN |
分类号 |
C07D251/44;B01D15/38;B01J20/286;B01J20/32;C07D251/50;C07D251/70;C07K1/20;G01N30/00 |
主分类号 |
C07D251/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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