发明名称 |
METHODS OF USING (+)-1,4-DIHYDRO-7-[(3S,4S)-3-METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL]-4-OXO-1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID FOR TREATMENT OF ANTECEDENT HEMATOLOGIC DISORDERS |
摘要 |
Methods of treating, preventing or managing antecedent hematologic disorders, such as myelodysplastic syndrome, including chronic myelomonocytic leukemia are disclosed. The methods encompass the administration of SNS-595. Also provided are methods of treatment using this compound with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy. In certain embodiments, the method of treatment comprise administering SNS-595 in combination with cytarabine. Pharmaceutical compositions and single unit dosage forms suitable for use in the methods are also disclosed. |
申请公布号 |
WO2009075841(A2) |
申请公布日期 |
2009.06.18 |
申请号 |
WO2008US13549 |
申请日期 |
2008.12.10 |
申请人 |
SUNESIS PHARMACEUTICALS, INC.;MICHELSON, GLENN |
发明人 |
MICHELSON, GLENN |
分类号 |
A61K31/4375;A61K31/513;A61K45/06;A61P35/02 |
主分类号 |
A61K31/4375 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|