| 摘要 |
PROBLEM TO BE SOLVED: To provide modified immunoglobulin-binding proteins, e.g., Staphylococcus protein A, having improved binding specificity for immunoglobulins, and methods of making and using the same.SOLUTION: A method of affinity-purifying one or more immunoglobulins from a sample comprises the steps of: (a) providing a sample comprising one or more immunoglobulins; (b) contacting the sample with a chromatography matrix under conditions that the one or more immunoglobulins bind to the matrix; and (c) recovering the one or more bound immunoglobulins by eluting under suitable conditions.SELECTED DRAWING: None |
