发明名称 (1H-AZOL-1-YLMETHYL) SUBSTITUTED QUINOLINE, QUINAZOLINE OR QUINOXALINE DERIVATIVES
摘要 (1H-azol-1-ylmethyl)substituted quinoline, quinazoline or quinoxaline derivatives, compositions containing the same, and methods of treating mammals suffering from disorders which are characterized by an excessive proliferation and/or abnormal differentiation of epithelial tissues. Process for preparing (1H-azol-1-ylmethyl) substituted quinoline, quinazoline or quinoxaline derivatives having the general formula I: (see formula I) wherein -X1=X2- is a bivalent radical, R is H or lower alkyl, Y is H or an alkyl, cycloalkyl, aromatic, substituted aromatic, alkenyl or alkynyl group, and Z is a quinoline, quinazoline or quinoxaline derivative.
申请公布号 CA2002864(C) 申请公布日期 1999.11.16
申请号 CA19892002864 申请日期 1989.11.14
申请人 发明人 FREYNE, EDDY J. E.;VENET, MARC G.;RAEYMAEKERS, ALFONS H. M.;SANZ, GERARD C.
分类号 C07D401/06;A61K31/00;A61K31/47;A61K31/4704;A61K31/4709;A61K31/495;A61K31/498;A61K31/505;A61K31/517;A61K31/529;A61P5/26;A61P35/00;A61P43/00;C07D401/14;C07D403/06;C07D403/14;C07D407/14;C07D409/14;C07D417/14;C07D521/00;(IPC1-7):C07D401/00 主分类号 C07D401/06
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