| 发明名称 | Interleukin-10 fusion proteins | ||
| 摘要 | The present invention generally relates to fusion proteins of antibodies and interleukin-10 (IL-10). In addition, the present invention relates to polynucleotides encoding such fusion proteins, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the fusion proteins of the invention, and to methods of using them in the treatment of disease. | ||
| 申请公布号 | US9346872(B2) | 申请公布日期 | 2016.05.24 |
| 申请号 | US201313959051 | 申请日期 | 2013.08.05 |
| 申请人 | ROCHE GLYCART AG | 发明人 | Duerner Lydia Jasmin;Emrich Thomas;Fischer Jens;Hosse Ralf;Moessner Ekkehard;Umana Pablo;Xu Daigen |
| 分类号 | C07K16/00;C07K14/54;A61K38/20;C07K16/40 | 主分类号 | C07K16/00 |
| 代理机构 | Jones Day | 代理人 | Jones Day |
| 主权项 | 1. A fusion protein comprising an antibody and an IL-10 molecule, wherein the antibody comprises the heavy chain variable region of SEQ ID NO: 67 and the light chain variable region of SEQ ID NO: 69, and wherein the IL-10 molecule comprises SEQ ID NO:1. | ||
| 地址 | Schlieren CH | ||