发明名称 |
C-Kit Modulators And Methods Of Use |
摘要 |
The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellu-lar activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Even more specifically, the invention provides compounds for modulating c-Kit kinase activity and methods of treating diseases mediated by c-Kit activity utilizing the compounds and pharmaceutical compositions thereof.
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申请公布号 |
US2008096892(A1) |
申请公布日期 |
2008.04.24 |
申请号 |
US20070569873 |
申请日期 |
2007.09.04 |
申请人 |
EXELIXIS, INC. |
发明人 |
CHENG WEI;WANG CO ERICK;KIM MOON HWAN;KLEIN RHETT RONALD;LE DONNA T.;TSUHAKO AMY LEW;NUSS JOHN M.;XU WEI;BAJJALIEH WILLIAM |
分类号 |
A61K31/498;A61K;A61K31/167;A61K31/41;A61K31/4192;A61K31/4196;A61K31/4406;A61K31/495;A61K31/505;C07C233/15;C07D213/30;C07D239/26;C07D241/42;C07D249/06;C07D249/08;C07D257/04;C07D403/04;C12N5/06;C12Q1/48;G01N33/566 |
主分类号 |
A61K31/498 |
代理机构 |
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代理人 |
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地址 |
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