| 发明名称 |
PLGA scaffold |
| 摘要 |
Disclosed is a PLGA (poly(D,L-lactide-co-glycolide)) cell scaffold. The cell scaffold is based on a PLGA scaffold, which is an FDA-approved material with no cytotoxicity, and overcomes the problem with conventional PLGA scaffolds of poor cell adhesion. |
| 申请公布号 |
US9345807(B2) |
申请公布日期 |
2016.05.24 |
| 申请号 |
US201414273557 |
申请日期 |
2014.05.09 |
| 申请人 |
DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY |
发明人 |
Jeon Won Bae;Choi Seong Kyoon |
| 分类号 |
A61L27/18;A61L27/54;A61L27/34;A61L27/56 |
主分类号 |
A61L27/18 |
| 代理机构 |
|
代理人 |
Bayramoglu Gokalp |
| 主权项 |
1. A method for fabricating a cell scaffold, comprising:
dissolving a PLGA (poly(D,L-lactide-co-glycolide)) substrate in an organic solvent to give a PLGA solution; and adding an effervescent agent to the PLGA solution to afford a PLGA scaffold with a porous structure; coating the PLGA scaffold with an elastin-like artificial extracellular matrix comprising a compound represented by the following General Formula 1:
TGPG[VGRGD(VGVPG)n]m [General Formula 1] wherein, n is an integer meeting 2<n<, and m is an integer meeting 10<m<30. |
| 地址 |
Daegu KR |
