| 发明名称 |
Fused pyrimidine derivatives for inhibition of tyrosine kinase activity |
| 摘要 |
The present invention relates to a novel fused pyrimidine derivative having an inhibitory activity for tyrosine kinases, and a pharmaceutical composition for preventing or treating cancers, tumors, inflammatory diseases, autoimmune diseases, or immunologically mediated diseases comprising same as an active ingredient. |
| 申请公布号 |
US9345719(B2) |
申请公布日期 |
2016.05.24 |
| 申请号 |
US201414521766 |
申请日期 |
2014.10.23 |
| 申请人 |
Hanmi Science Co., Ltd. |
发明人 |
Cha Mi Young;Kang Seok Jong;Kim Mi Ra;Lee Ju Yeon;Jeon Ji Young;Jo Myoung Gi;Kwak Eun Joo;Lee Kwang Ok;Ha Tae Hee;Suh Kwee Hyun;Kim Maeng Sup |
| 分类号 |
C07D491/04;A61K31/519;A61K31/675;A61K31/5377;A61K31/541;A61K31/55;A61K31/553;C07D495/04;C07D491/048;C07F9/6561;A61K31/538;A61K45/06;C07D493/04;C07D519/00;C07F9/38;A61P25/28;A61P25/16;A61P19/02;A61P11/06;A61P35/04;A61K35/02;A61P37/06 |
主分类号 |
C07D491/04 |
| 代理机构 |
|
代理人 |
Wood Dan L. |
| 主权项 |
1. A compound of formula (I) or a pharmaceutically acceptable salt thereof: wherein, W is O; X is O, NH, S, SO or SO2; Y is hydrogen atom, halogen atom, C1-6alkyl or C1-6alkoxy; A and B are each independently hydrogen atom, halogen atom, or di(C1-6alkyl)aminomethyl; Z is selected from the group consisting of formulae Z1 to Z203: |
| 地址 |
Hwaseong-Si KR |
