| 发明名称 | Compounds for enhancing arginase activity and methods of using same | ||
| 摘要 | The present invention relates to a method for enhancing arginase activity in a damaged or injured cell. In other aspects, the invention provides a method for treating a disorder that can be treated by enhancing arginase activity in a human in need thereof, the method comprising administering to the human an effective amount of a compound that enhances arginase activity. Such disorders include ischemia, hypoxia, neurodegenerative disease or condition, stroke or trauma of the nervous system. In yet another aspect, the invention provides methods for promoting regeneration of a neural cell in a human in need thereof. | ||
| 申请公布号 | US9345694(B2) | 申请公布日期 | 2016.05.24 |
| 申请号 | US201213416885 | 申请日期 | 2012.03.09 |
| 申请人 | Cornell Research Foundation, Inc.;The Research Foundation of the City University of New York | 发明人 | Ratan Rajiv R.;Filbin Marie T. |
| 分类号 | A61K31/4439;A61K31/05;A61K31/085;A61K31/122;A61K31/352;A61K31/4184;A61K31/36;A61K31/7048 | 主分类号 | A61K31/4439 |
| 代理机构 | Hoffman & Baron, LLP | 代理人 | Hoffman & Baron, LLP |
| 主权项 | 1. A method for treating a disorder that can be treated by enhancing arginase activity in a human in need thereof, the method consisting of administering to the human an effective amount of Lansoprazole, or a pharmaceutically acceptable salt of such compound, and a carrier and/or excipient, wherein the disorder is stroke. | ||
| 地址 | Ithaca NY US | ||