发明名称 HETEROLOGOUS EXPRESSION OF NEISSERIAL PROTEINS
摘要 PROBLEM TO BE SOLVED: To provide alternative or improved approaches to the heterologous expression of the proteins of Neisseria meningitidis and Neisseria gonorrhoeae, the approaches typically affecting the level of expression, the ease of purification, the cellular localization, and/or the immunological properties of the expressed protein.SOLUTION: For example, the invention provides a method for the heterologous expression of a protein of the invention, in which (a) at least one domain in the protein is deleted and, optionally, (b) no fusion partner is used.SELECTED DRAWING: Figure 8
申请公布号 JP2016128520(A) 申请公布日期 2016.07.14
申请号 JP20160078708 申请日期 2016.04.11
申请人 NOVARTIS VACCINES & DIAGNOSTICS SRL 发明人 ARICO MARIA BEATRICE;COMANDUCCI MAURIZIO;GALEOTTI CESIRA;MASIGNANI VEGA;GIULIANI MARZIA MONICA;PIZZA MARIAGRAZIA
分类号 C07K14/22;C12N15/09;A61K38/00;C07K19/00;C12P21/02;C12Q1/68 主分类号 C07K14/22
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