| 发明名称 |
DIMERIC BACTERIOPHAGE LYSINS |
| 摘要 |
The present invention provides isolated dimeric Streptococcus-specific phage lysins having two Streptococcus-specific phage lysin monomers covalently linked to each other, and having killing activity against one or more Streptococcus bacteria. Also provided for are pharmaceutical compositions of dimeric lysins and their use in therapeutic treatment or alleviation of infections or bacterial colonizations. The dimeric lysins may also be used to decontaminate porous and non-porous surfaces or devices. |
| 申请公布号 |
US2016208231(A1) |
申请公布日期 |
2016.07.21 |
| 申请号 |
US201615007445 |
申请日期 |
2016.01.27 |
| 申请人 |
Fischetti Vincent A.;Resch Gregory |
发明人 |
Fischetti Vincent A.;Resch Gregory |
| 分类号 |
C12N9/36;C12N7/00;A01N63/02 |
主分类号 |
C12N9/36 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. An isolated dimeric Streptococcus-specific phage lysin comprising two Streptococcus-specific phage lysin monomers covalently linked to each other, wherein said dimer has killing activity against one or more Streptococcus bacteria. |
| 地址 |
West Hempstead NY US |
