| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide improved methods to produce peptides or peptidomimetics that possess increased conformational rigidity, metabolic stability and cell penetrability. <P>SOLUTION: The present invention provides new peptidomimetic macrocycles and methods for their preparation and use, as well as amino acid analogs and macrocycle-forming linkers, and kits useful in their production. <P>COPYRIGHT: (C)2012,JPO&INPIT |
