发明名称 |
ANTIBODIES DIRECTED AGAINST LYMPHOCYTE ACTIVATION GENE 3 (LAG-3) |
摘要 |
The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a protein encoded by the Lymphocyte Activation Gene-3 (LAG-3). The invention provides a LAG-3-binding agent that comprises the aforementioned immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide. The invention also provides related vectors, compositions, and methods of using the LAG-3-binding agent to treat a disorder or disease that is responsive to LAG-3 inhibition, such as cancer or an infectious disease. |
申请公布号 |
WO2016126858(A2) |
申请公布日期 |
2016.08.11 |
申请号 |
WO2016US16424 |
申请日期 |
2016.02.03 |
申请人 |
ANAPTYSBIO, INC. |
发明人 |
JUN, HELEN TONI;KEHRY, MARILYN;BOWERS, PETER;KING, DAVID J. |
分类号 |
A61K39/395;C07K16/30 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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