发明名称 SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINE SYNTHESIS
摘要 PROBLEM TO BE SOLVED: To provide methods for producing substituted heterocycle fused gamma-carbolines, intermediates useful in producing them, methods for producing such intermediates and such heterocycle fused gamma-carbolines.SOLUTION: The invention provides compounds represented by formula 1C in the figure and methods for producing the same. Preferably, A is Cl or Br, and Rto Rare H. (A is halogen; Rto Rare each independently substituted/unsubstituted alkyl, alkenyl, cycloalkyl, heterocycloalkyl, hydroxy, nitro, aryl, heteroaryl or the like; k is 1 or 2; and m is an integer from 0 to 2.)SELECTED DRAWING: None
申请公布号 JP2016155849(A) 申请公布日期 2016.09.01
申请号 JP20160077538 申请日期 2016.04.07
申请人 INTRA-CELLULAR THERAPIES INC 发明人 JOHN CHARLES TOMESCH;LI PENG;YAO WEI;ZHANG QIAN;JAMES DAVID BEARD;ANDREW S THOMPSON;CHENG HUA
分类号 C07D471/04;A61K31/437;A61K31/4985;A61P1/04;A61P3/04;A61P15/10;A61P25/00;A61P25/04;A61P25/06;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P43/00;B01J31/30;C07B53/00;C07B57/00 主分类号 C07D471/04
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