Methods and materials for identifying and treating mammals having HER2-positive breast cancer

摘要

This document provides methods and materials involved in identifying mammals having breast cancer (e.g., HER2-positive breast cancer) responsive to trastuzumab as well as methods and materials involved in treating mammals having breast cancer (e.g., HER2-positive breast cancer) responsive to trastuzumab. For example, methods and materials for using expression level profiles to identify mammal having HER2-positive breast cancer with an increased likelihood of being responsive to trastuzumab are provided.