Synthetic compounds for vegetative ABA responses

摘要

The present invention provides agonist compounds that active ABA receptors, and agricultural formulations comprising the agonist compounds. The agricultural formulations are useful for inducing ABA responses in plant vegetative tissues, reducing abiotic stress in plants, and inhibiting germination of plant seeds. The compounds are also useful for inducing expression of ABA-responsive genes in cells that express endogenous or heterologous ABA receptors.

主权项

1. An agricultural formulation, comprising a compound of Formula I:wherein
R1 is selected from the group consisting of H, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, cycloalkyl, heterocycloalkyl, aryl and heteroaryl, R2 is selected from the group consisting of cycloalkyl, heterocycloalkyl, aryl and heteroaryl, each optionally substituted with from 1-4 R2a groups, each R2a is independently selected from the group consisting of H, halogen, C1-6 alkyl, C1-6 alkoxy, C1-6 haloalkyl, C1-6 haloalkoxy, C2-6 alkenyl, C2-6 alkynyl, —OH, C1-6 alkylhydroxy, —CN, —NO2, —C(O)R2b, —C(O)OR2b, —OC(O)R2b, —C(O)NR2bR2c, —NR2bC(O)R2c, —SO2R2b, —SO2OR2b, —SO2NR2bR2c, and —NR2bSO2R2c, each of R2b and R2c are independently selected from the group consisting of H and C1-6 alkyl, each of R3, R4 and R5 are independently selected from the group consisting of H and C1-6 alkyl, L is a linker selected from the group consisting of a bond and C1-6 alkylene, subscript m is an integer from 0 to 4, subscript n is an integer from 0 to 3, or a salt or isomer thereof.