Combination of therapeutic agents for treating cancer
摘要
A combination therapy for treating patients suffering from proliferative diseases or diseases associated with persistent angiogenesis is disclosed. The patient is treated with a camptothecin derivative and one or more chemotherapeutic agents selected from a microtubule active agent; an alkylating agent; an anti-neoplastic anti-metabolite; a platin compound; a topoisomerase II inhibitor; a VEGF inhibitor; a tyrosine kinase inhibitor; an EGFR kinase inhibitor; an mTOR kinase inhibitor; an insulin-like growth factor I inhibitor; a Raf kinase inhibitor; a monoclonal antibody; a proteasome inhibitor; a HDAC inhibitor; and ionizing radiation.
申请公布号
ZA200704701(B)
申请公布日期
2008.09.25
申请号
ZA20070004701
申请日期
2007.06.07
申请人
NOVARTIS AG SIGMA-TAU INDUSTRIE FARMACEUTTICHE RIUNITE S.P.A.