The present invention concerns a method for identifying compounds that decrease the ability of Human Immunodeficiency Virus (HIV) to enter previously uninfected cells. More specifically it relates to a homogeneous competitive cell-based binding assay for the identification of HIV-1 entry fusion inhibitors on a high content screening platform or flow cytometric-based read out.
申请公布号
CA2694278(A1)
申请公布日期
2009.01.29
申请号
CA20082694278
申请日期
2008.07.25
申请人
TIBOTEC PHARMACEUTICALS LTD.
发明人
VAN ACKER, KOENRAAD, LODEWIJK, AUGUST;MEERSSEMAN, GEERT HENRI;DAMS, GERY KAREL JULIA;OHAGEN, ASA CATRINE;BUNKENS, LIEVE ELISABETH LOUIS;HOLEMANS, PASCALE ALICE JAN