SKIN TREATMENT

摘要

Collagen is treated with a water-soluble compound which, in the free acid form, is of formula (1) wherein: L is an organic linking group; W is a covalent bond, -O-, -S-, -SO-, SO2-, -SO2NR<1>-, -NR<1>-, -NR<1>CO(CH2)p-, -NR<1>CONR<1>-, -NR<1>CH2CONR<1>-, -CONR<1>-, -CH=CH-, -(CH2)p-, or (CH2)p-NR<1>-; Y is a reactive group which comprises a heterocyclic reactive group, an activated vinyl group or a group convertible on treatment with aqueous alkali to an activated vinyl group, each R<1> independently is H or C1-4-alkyl; m and n each independently have a value of 0 or 1; and p has a value of 1 to 4; provided that when a compound of formula (1) has four or more carboxy groups its molecular weight is below 500.