NOVEL FLUORESCENTLY LABELED SPHINGOMYELIN AND USE THEREOF

摘要

A compound represented by formula (1) (wherein A represents a residue of a water-soluble fluorescence-emitting compound; B and E represent linkers which are the same as or different from each other; R1 to R4 independently represent a hydrogen atom or an alkyl group which may be substituted; X represents 3 to 50; m and n independently represent 10 to 30; and the group represented by formula (2) represents a single bond or a double bond) is novel fluorescently labeled sphingomyelin that exhibits the same behavior as that of native sphingomyelin. The use of the fluorescently labeled sphingomyelin makes it possible to provide: a lipid raft visualizing agent, a diagnosis marker for a lipid raft-related disease, a reagent for detecting or quantifying a lipid raft, and a method for visualizing a lipid raft.