SURFACE FUNCTIONALIZED, HOST-GUEST POLYMER NANO-ASSEMBLIES AND METHODS THEREOF

摘要

The invention generally relates to polymer-based nano-structures. More particularly, the invention relates to novel, surface-functionalized, guest-host polymer nano-assemblies and nano-delivery vehicles useful in diverse fields including drug delivery, diagnostics and specialty materials. The nano-assemblies and nano-delivery vehicles of the invention are afforded via simplify and reliable approaches.

主权项

1. A nano-assembly comprising:
a host crosslinked polymer network having a functionalized surface with one or more functional groups; and a guest molecular cargo non-covalently encapsulated in the host crosslinked polymer network,wherein the host crosslinked polymer network is addressable by a biological or chemical intervention resulting in partial or complete decrosslinking of the host polymer network and release of the guest molecular cargo from the nano-assembly.