发明名称 |
CULTURING PLURIPOTENT STEM CELLS |
摘要 |
A method for culturing and maintaining a pluripotent stem cell in an undifferentiated state is provided. The method comprises culturing the pluripotent stem cell in a medium comprising an MEK inhibitor, a GSK3 inhibitor, a dual inhibitor of AMPK and/or BMP signaling and LIF. A cell produced by the method, cell culture medium and a kit for performing the method described is also provided. |
申请公布号 |
US2016319240(A1) |
申请公布日期 |
2016.11.03 |
申请号 |
US201415031614 |
申请日期 |
2014.10.27 |
申请人 |
Agency for Science, Technology and Research |
发明人 |
CHAN Yun Shen;NG Huck Hui |
分类号 |
C12N5/0735 |
主分类号 |
C12N5/0735 |
代理机构 |
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代理人 |
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主权项 |
1. A method for culturing and maintaining a pluripotent stem cell in an undifferentiated state comprising culturing the pluripotent stem cell in a medium comprising an MEK inhibitor, a GSK3 inhibitor, a dual inhibitor of AMPK and/or BMP signaling and LIF. |
地址 |
Singapore SG |