SUBSTITUTED 2-INDOLINONE AS PTK INHIBITORS CONTAINING A ZINC BINDING MOIETY
摘要
<p>The present invention relates to substituted 2-indolinone containing zinc- binding moiety based derivatives that have enhanced or unique properties as inhibitors of protein tyrosine kinase (PTK) receptors and their use in the treatment of PTK related diseases and disorders such as cancer. The said derivatives may further act as HDAC inhibitors.</p>
申请公布号
WO2008033743(A1)
申请公布日期
2008.03.20
申请号
WO2007US77964
申请日期
2007.09.10
申请人
CURIS, INC.;CAI, XIONG;QIAN, CHANGGENG;GOULD, STEPHEN