发明名称 OPHTHALMIC COMPOSITIONS CONTAINING A NITRIC OXIDE DONOR
摘要 The present invention relates to compositions comprising a 4-nitrooxybutan-1-ol alkyl ester as nitric oxide donor. More specifically, the invention relates to compositions comprising 4-nitrooxybutan-1-ol alkyl ester as a nitric oxide donor and an ophthalmic drug, useful in controlling elevated intraocular pressure associated with glaucoma or ocular hypertension associated with other diseases or conditions. The invention is also directed to methods of controlling intraocular pressure utilizing said compositions.
申请公布号 US2016158182(A1) 申请公布日期 2016.06.09
申请号 US201414904747 申请日期 2014.07.07
申请人 NICOX SCIENCE IRELAND 发明人 ONGINI Ennio;ALMIRANTE Nicoletta;STORONI Laura;BASTIA Elena
分类号 A61K31/22;C07C203/04;A61K9/00;A61K45/06 主分类号 A61K31/22
代理机构 代理人
主权项
地址 Dublin IE