发明名称 |
METHOD OF REDUCING MULTI-DRUG RESISTANCE USING INOSITOL TRIPYROPHOSPHATE |
摘要 |
Inositol trisphosphate (ITPP) causes normalization of tumor vasculature and is a particularly effective cancer therapy when a second chemotherapeutic agent is administered following partial vascularization. ITPP also treats, alone or in combination, multi-drug resistant cancers. ITPP can also be used to reduce the amount of a second chemotherapeutic drug required for anticancer activity. In addition, ITPP enhances immune response and treats hyperproliferative disorders. |
申请公布号 |
US2016235771(A1) |
申请公布日期 |
2016.08.18 |
申请号 |
US201615145257 |
申请日期 |
2016.05.03 |
申请人 |
NORMOXYS, INC. ;UNIVERSITE DE STRASBOURG |
发明人 |
Nicolau Yves Claude;Lehn Jean-Marie;Kieda Claudine |
分类号 |
A61K31/6615;A61K31/7068;A61K45/06;A61K33/24;A61K31/337 |
主分类号 |
A61K31/6615 |
代理机构 |
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代理人 |
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主权项 |
1. A method for treating cancer, comprising
administering to a subject in need thereof a therapeutically effective amount of ITPP; and administering to the subject a therapeutically effective amount of a chemotherapeutic agent following the partial vascular normalization in the tumor. |
地址 |
Brighton MA US |