发明名称 METHOD OF REDUCING MULTI-DRUG RESISTANCE USING INOSITOL TRIPYROPHOSPHATE
摘要 Inositol trisphosphate (ITPP) causes normalization of tumor vasculature and is a particularly effective cancer therapy when a second chemotherapeutic agent is administered following partial vascularization. ITPP also treats, alone or in combination, multi-drug resistant cancers. ITPP can also be used to reduce the amount of a second chemotherapeutic drug required for anticancer activity. In addition, ITPP enhances immune response and treats hyperproliferative disorders.
申请公布号 US2016235771(A1) 申请公布日期 2016.08.18
申请号 US201615145257 申请日期 2016.05.03
申请人 NORMOXYS, INC. ;UNIVERSITE DE STRASBOURG 发明人 Nicolau Yves Claude;Lehn Jean-Marie;Kieda Claudine
分类号 A61K31/6615;A61K31/7068;A61K45/06;A61K33/24;A61K31/337 主分类号 A61K31/6615
代理机构 代理人
主权项 1. A method for treating cancer, comprising administering to a subject in need thereof a therapeutically effective amount of ITPP; and administering to the subject a therapeutically effective amount of a chemotherapeutic agent following the partial vascular normalization in the tumor.
地址 Brighton MA US
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