发明名称 |
2-BENZIMIDAZOLYL-6-MORPHOLINO-4-PHENYLPYRIMIDINE DERIVATIVES AS PI3K AND MTOR INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS |
摘要 |
<p>The invention concerns pyrimidine derivatives of Formula (I), wherein each of p, R<SUP>1</SUP>, R<SUP>2</SUP>, q, R<SUP>3</SUP>, r, R<SUP>4</SUP>, X<SUP>1</SUP> and Q<SUP>1</SUP> have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in a method for producing an anti-proliferative effect in a warm blooded animal such as man.</p> |
申请公布号 |
WO2008032086(A1) |
申请公布日期 |
2008.03.20 |
申请号 |
WO2007GB03490 |
申请日期 |
2007.09.12 |
申请人 |
ASTRAZENECA AB;ASTRAZENECA UK LIMITED;BUTTERWORTH, SAM;GRIFFEN, EDWARD, JOLYON;PASS, MARTIN |
发明人 |
BUTTERWORTH, SAM;GRIFFEN, EDWARD, JOLYON;PASS, MARTIN |
分类号 |
C07D401/14;A61K31/495;A61P35/00;C07D403/04;C07D403/14;C07D413/14 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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