发明名称 |
USE OF THE EDA DOMAIN OF FIBRONECTIN |
摘要 |
This invention relates to the use of a polypeptide in the production of an immunostimulatory agent, said polypeptide comprising a sequence corresponding to the EDA domain of fibronectin, a fragment of the EDA domain which can bind to TLR4 or a variant of said EDA domain or a fragment which can bind to TLR4 and which has a homology of more than 70% with any form or natural fragment of the EDA domain. The invention also relates to the production methods and applications of said agent. |
申请公布号 |
PT1913954(E) |
申请公布日期 |
2012.11.19 |
申请号 |
PT20060794018T |
申请日期 |
2006.06.13 |
申请人 |
PROYECTO DE BIOMEDICINA CIMA, S.L. |
发明人 |
CLAUDE LECLERC;JESUS PRIETO VALTUENA;JUAN JOSE LASARTE SAGASTIBELZA;MARTA GORRAIZ AYALA |
分类号 |
A61K38/39;A61P37/04;C07K14/18;C07K14/78;C07K19/00 |
主分类号 |
A61K38/39 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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