发明名称 |
OPTICAL PROBE FOR THROMBIN |
摘要 |
Optical probes are presented, the probes comprising a first probe element, and a second probe element connected to a core. The first probe element comprises a first fluorophore connected to a first quencher by a first cleavable linker. The second probe element comprises a second fluorophore connected to a second quencher by a second cleavable linker. The first fluorophore is separated from the first quencher when the first cleavable linker is cleaved, and the second fluorophore is separated from the second quencher when the second cleavable linker is cleaved. Methods of detecting a first and second enzyme using the optical probe are also presented. |
申请公布号 |
WO2016151297(A1) |
申请公布日期 |
2016.09.29 |
申请号 |
WO2016GB50763 |
申请日期 |
2016.03.18 |
申请人 |
THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH |
发明人 |
BRADLEY, Mark;CHANKESHWARA, Sunay Vijaykumar;MEGIA-FERNANDEZ, Alicia |
分类号 |
A61K49/00;G01N21/00;G01N21/64;G01N33/574 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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