| 发明名称 |
DT-diaphorase directed anti-tumor agents |
| 摘要 |
The present invention relates to a novel benzoquinone, 2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone and its esters. The compounds can be used to treat tumors exhibiting elevated levels of the enzyme DT-diaphorase.
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| 申请公布号 |
US6156744(A) |
申请公布日期 |
2000.12.05 |
| 申请号 |
US19990317906 |
申请日期 |
1999.05.24 |
| 申请人 |
CANCER RESEARCH CAMPAIGN TECH (LONDON);UNIVERSITY TECHNOLOGY CORP.;UNIVERSITY OF SALFORD |
发明人 |
ROSS, DAVID;BUTLER, JOHN;HARGREAVES, ROBERT H. J.;SIEGEL, DAVID;BEALL, HOWARD D. |
| 分类号 |
C07D203/08;(IPC1-7):A61K31/396;C07D403/02;C07D403/08 |
主分类号 |
C07D203/08 |
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