| 发明名称 |
Low-Sodium Effervescent Pharmaceutical Formulations |
| 摘要 |
A stable effervescent tablet granule or powder composition free from excipients that may react with an effervescing organic acid component, comprising: an effective amount of a antidiabetic drug, an effervescing organic acid component, an effervescing base component; buffers, to modulate gastric ρïí after ingestion, essentially free of solium; wherein said composition is completely solubilised within 5 minutes without stirring in 3 to 8 fluid ounces of water at between 5-20° C. |
| 申请公布号 |
US2016220481(A1) |
申请公布日期 |
2016.08.04 |
| 申请号 |
US201415021214 |
申请日期 |
2014.03.01 |
| 申请人 |
EFFRX PHARMACEUTICALS SA |
发明人 |
SCHMIDT TIMO;HAYWARD MARSHALL A. |
| 分类号 |
A61K9/46;A61K31/7042;A61J3/10;A61K31/403;A61K9/20;A61K31/155;A61K31/4985 |
主分类号 |
A61K9/46 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A stable effervescent tablet, granule or powder composition free from sodium introduced by the effervescing couple, comprising;
an effective amount of one or more antidiabetic compounds; an effervescing acid component essentially free of sodium, an effervescing base component essentially free of sodium: and buffers, to modulate gastric pH after ingestion, essentially free of sodium; wherein said composition is completely solubilised within 5 minutes without stirring in 3 to 8 fluid ounces of water at between 5-20° C. |
| 地址 |
Freienbach CH |
