| 发明名称 |
INFLUENZA VIRUS REPLICATION BY INHIBITING MICRORNA LEC7C BINDING TO INFLUENZA VIRAL CRNA AND MRNA |
| 摘要 |
A vector, composition and method to improve influenza virus replication by inhibiting miRNA lec-7C binding to influenza virus mRNA and/or cRNA. |
| 申请公布号 |
US2016355790(A1) |
申请公布日期 |
2016.12.08 |
| 申请号 |
US201615170556 |
申请日期 |
2016.06.01 |
| 申请人 |
Wisconsin Alumni Research Foundation |
发明人 |
Kawaoka Yoshihiro;Neumann Gabriele;Ping Jihui |
| 分类号 |
C12N7/00;A61K39/145;C07K14/005 |
主分类号 |
C12N7/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A recombinant vector comprising an influenza M gene segment having a nucleotide other than U/T at position 1011, a nucleotide other than G at position 1012, a nucleotide other than A at position 1013, a nucleotide other than U/T at position 1014, a nucleotide other than G at position 1015, a nucleotide other than G at position 1016, a nucleotide other than A at position 1017, or any combination thereof, wherein the numbering refers to cRNA+. |
| 地址 |
Madison WI US |
