发明名称 |
Glycoconjugates of modified camptothecin derivatives (A-or B-ring linkage) |
摘要 |
PCT No. PCT/EP97/05089 Sec. 371 Date Mar. 24, 1999 Sec. 102(e) Date Mar. 24, 1999 PCT Filed Sep. 17, 1997 PCT Pub. No. WO98/14468 PCT Pub. Date Apr. 9, 1998The present invention relates to glycoconjugates of camptothecin derivatives in which at least one carbohydrate component is linked via suitable spacers with the A or B ring of a camptothecin derivative. The invention furthermore relates to processes for preparing the compounds according to the invention and to their use as medicaments, in particular in connection with cancer.
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申请公布号 |
US6156754(A) |
申请公布日期 |
2000.12.05 |
申请号 |
US19990269314 |
申请日期 |
1999.03.24 |
申请人 |
BAYER AKTIENGESELLSCHAFT |
发明人 |
LERCHEN, HANS-GEORG;VON DEM BRUCH, KARSTEN;BAUMGARTEN, JOERG;SPERZEL, MICHAEL |
分类号 |
A61K38/00;A61P35/00;C07K5/06;C07K5/08;C07K9/00;(IPC1-7):A61K31/50;A61K31/44;C07D471/00;C07D401/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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