发明名称 |
Use of a CB1 Antagonist for Treating Side Effects and Negative Symptoms of Schizophrenia |
摘要 |
The present invention discloses and claims a method of treating cognition deficits in a patient suffering from schizophrenia by administering to said patient a therapeutically effective amount of a CB1 receptor antagonist as described herein. In another aspect, this invention also discloses and claims a combination of one or more CB1 receptor antagonists and of one or more antipsychotic agents useful in the treatment of psychiatric disorders. The combination of this invention provides synergistic results in that the combination improves positive and negative symptoms of schizophrenia, weight gain and catalepsy.
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申请公布号 |
US2008221078(A1) |
申请公布日期 |
2008.09.11 |
申请号 |
US20080125285 |
申请日期 |
2008.05.22 |
申请人 |
AVENTIS PHARMACEUTICALS INC. |
发明人 |
BLACK MARK;BOROWSKY BETH;ROGACKI NANCY;SENYAH YAW;STEVENS RACHEL |
分类号 |
A61K31/397;A61P25/18;C07D205/04;C07D215/36;C07D239/24;C07D401/04 |
主分类号 |
A61K31/397 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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