发明名称 METHOD OF ESTIMATING SECONDARY STRUCTURE IN RNA AND PROGRAM AND APPARATUS THEREFOR
摘要 Supposing a frame (F) having a definite short length (L2) on a transcript, the frame (F) is shifted finely stepwise at constant intervals (t). Thus, the structures in the individual micro sections are successively analyzed and the first probability in a specific secondary structure at a specific position in each micro section is determined. Next, one or more specific positions clarified in the individual micro sections are correspondingly located on the original transcript and the degree of the overlap between the individual specific positions is referred to as the second probability. By paying attention to these two probabilities, it can be estimated at an elevated reliability whether or not a desired secondary structure occurs in practice in an RNA such as an mRNA.
申请公布号 WO2008072713(A9) 申请公布日期 2008.09.25
申请号 WO2007JP74063 申请日期 2007.12.13
申请人 TAKEDA PHARMACEUTICAL COMPANY LIMITED;NAKAMURA, SHINGO 发明人 NAKAMURA, SHINGO
分类号 C12N15/09;G06F19/16;G06F19/26;G06Q50/00 主分类号 C12N15/09
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