| 发明名称 |
Potassium channel inhibitors and method |
| 摘要 |
Indanes, benzopyrans and analogues thereof are potassium channel inhibitors and blockers of IKur and have the structure where A, B, D, Q, X1, R, R1, X2 and R2 are as defined herein. These compounds are useful as antiarrhythmic agents. In addition, a method is provided for preventing cardiac arrhythmia employing the above compounds.
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| 申请公布号 |
US6150356(A) |
申请公布日期 |
2000.11.21 |
| 申请号 |
US19990375955 |
申请日期 |
1999.08.17 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
LLOYD, JOHN;FINLAY, HEATHER J.;VACCARO, WAYNE;ATWAL, KARNAIL S.;GROSS, MICHAEL F.;SPEAR, KERRY L. |
| 分类号 |
A61K31/277;A61K31/352;A61K31/353;A61K31/381;A61K31/42;A61K31/429;A61K31/436;A61K31/472;A61K31/496;A61K31/506;A61P9/06;C07C303/40;C07C311/20;C07D215/42;C07D311/68;C07D401/12;C07D405/12;C07D405/14;C07D407/12;C07D409/12;C07D409/14;C07D413/04;C07D413/14;C07D417/12;C07D473/38;C07D491/04;C07D491/052;C07D493/04;C07D513/04;(IPC1-7):C07D215/42 |
主分类号 |
A61K31/277 |
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