Method and system for sequencing nucleic acid molecules using sequencing by hybridization and comparison with decoration patterns

摘要

Various embodiments of the present invention are directed to methods and systems for sequencing a target molecule. In one embodiment of the present invention, a spectrum of the target molecule is determined. A decoration pattern of the target molecule is determined using physical methods. One or more candidate molecule sequences are determined based on having nucleic acid sequences that are consistent with the spectrum and the decoration pattern of the target molecule.