发明名称 METHODS AND COMPOSITIONS FOR RAISING LEVELS AND RELEASE OF GAMMA AMINOBUTYRIC ACID
摘要 The present invention provides methods of increasing the level or release of gamma aminobutyric acid (GABA) in the brain, treating Alzheimer's disease, Huntington's disease, symptoms thereof, anxiety, aggression, insomnia, cognitive or memory disturbances; seizures of any cause (e.g. idiopathic epilepsy), primary or metastatic brain tumors, depression (e.g. bipolar depression), or pain (e.g. neuropathic pain), comprising administration of glutamine, a salt thereof, or a glutamine-rich peptide. The present invention also provides methods for decreasing the level or release of GABA in the brain and treating hepatic encephalopathy, depressed consciousness, and coma, comprising decreasing dietary intake of glutamine.
申请公布号 WO2007059031(A3) 申请公布日期 2007.09.20
申请号 WO2006US43988 申请日期 2006.11.13
申请人 MASSACHUSETTS INSTITUTE OF TECHNOLOGY;WURTMAN, DICK;WANG, LEI 发明人 WURTMAN, DICK;WANG, LEI
分类号 A61K35/18;C07K1/00 主分类号 A61K35/18
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