发明名称 |
Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery |
摘要 |
The present invention relates to an amphiphilic block copolymer of a hydrophilic block and a hydrophobic block with a terminal hydroxyl group wherein the terminal hydroxyl group of the hydrophobic bock is substituted with a tocopherol or cholesterol group. It also relates to polymeric compositions capable of forming stable micelles in an aqueous solution, comprising the amphiphilic block copolymer and a polylactic acid derivative wherein one or more ends of the polylactic acid are covalently bound to at least one carboxyl group.
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申请公布号 |
US8349306(B2) |
申请公布日期 |
2013.01.08 |
申请号 |
US20070974196 |
申请日期 |
2007.10.10 |
申请人 |
SAMYANG BIOPHARMACEUTICALS CORPORATION;SEO MIN HYO;LEE SA-WON;HYUN MYUNG-HAN;YU JEONG-IL;CHANG DONG-HOON;YOON HYE-JEONG;KIM JEONG-KYUNG |
发明人 |
SEO MIN HYO;LEE SA-WON;HYUN MYUNG-HAN;YU JEONG-IL;CHANG DONG-HOON;YOON HYE-JEONG;KIM JEONG-KYUNG |
分类号 |
A61K31/74;A61K31/785;C08L39/04 |
主分类号 |
A61K31/74 |
代理机构 |
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地址 |
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