| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a compound having DNA synthase inhibitory activity, and to provide a pharmaceutical composition (a DNA synthase inhibitor and an anticancer drug) containing the compound as an active ingredient. <P>SOLUTION: The compound is expressed by general formula (1). In the formula, R1 and R2 are different from each other, representing a hydrogen atom or a benzoyl group in which the second position is substituted with a methyl group, the fourth and the sixth positions are substituted with a specified substituent such as a hydroxy group and an alkoxy group; and R3 represents an alkenyl group optionally having a hydroxy group. The pharmaceutical composition containing the above compound as an active ingredient is also provided. <P>COPYRIGHT: (C)2013,JPO&INPIT |
