Devices, compositions and methods for bone and tissue augmentation

摘要

Various polymeric materials and delivery systems are described, along with systems and methods for using them for bone and tissue augmentation, such as for the stabilization and/or correction of spinal compression fractures.

主权项

1. A structural alloplastic bone graft composition for augmentation, repair and/or fusion of bone, comprising:
(i) a biodegradable side chain crystallizable polymer having a first order transition above the body temperature of a patient, the biodegradable side chain crystallizable polymer having a flowable property at a delivery temperature above the transition temperature, the delivery temperature sufficiently low to avoid damage to tissue adjacent a delivery site with the patient's body; (ii) an osteoconductive material; and (iii) an osteoinductive material,
wherein the side chain crystallizable polymer comprises an amount of polar groups selected to increase the adhesion of the side chain crystallizable polymer to a bone tissue.