发明名称 COMBINATION THERAPY OF HSP90 INHIBITORS AND PD-1 INHIBITORS FOR TREATING CANCER
摘要 A pharmaceutical composition comprising a PD-1 inhibitor and a Hsp90 inhibitor, or a tautomer, or a pharmaceutically acceptable salt thereof, wherein the Hsp90 inhibitor is 3- (2,4-dihydroxy-5-isopropyl-phenyl)-4-(l-methyl-indol-5-yl)-5-hydroxy-[l,2,4] triazole or 5- hydroxy-4-(5-hydroxy-4-(l-methyl-lH-indol-5-yl)-4H-l,2,4-triazol-3-yl)-2-isopropylphenyl dihydrogen phosphate. Also provided is a method for treating cancer in a subject in need thereof, using the pharmaceutical composition described herein.
申请公布号 WO2016130502(A1) 申请公布日期 2016.08.18
申请号 WO2016US17075 申请日期 2016.02.09
申请人 SYNTA PHARMACEUTICALS CORP. 发明人 PROIA, David A.;RAO, Patricia E.
分类号 A61K39/395;A61K31/4196;A61K31/6615;A61P35/00 主分类号 A61K39/395
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