1-(HET)ARYLSULFONYL-(PYRROLIDINE OR PIPERIDINE)-2-CARBOXAMIDE DERIVATIVES AND THEIR USE AS TRPA1 ANTAGONISTS,申请号WO2016EP52950-传众专利搜索

发明名称	1-(HET)ARYLSULFONYL-(PYRROLIDINE OR PIPERIDINE)-2-CARBOXAMIDE DERIVATIVES AND THEIR USE AS TRPA1 ANTAGONISTS
摘要	The invention is concerned with the compounds of formula I and salts thereof and other compounds of formulas II-IX as disclosed herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formulas I-IX as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain or asthma.
申请公布号	WO2016128529(A1)	申请公布日期	2016.08.18
申请号	WO2016EP52950	申请日期	2016.02.12
申请人	F. HOFFMANN-LA ROCHE AG;GENENTECH, INC.	发明人	ESTRADA, Anthony;VOLGRAF, Matthew;CHEN, Huifen;KOLESNIKOV, Aleksandr;VILLEMURE, Elisia;VERMA, Vishal;WANG, Lan;SHORE, Daniel;DO, Steven;YUEN, Po-wai;HU, Baihua;WU, Guosheng;LIN, Xingyu;LU, Aijun
分类号	C07D403/12;A61K31/402;A61K31/4025;A61K31/4545;A61P11/00;A61P11/06;A61P11/14;A61P17/04;A61P19/02;A61P27/16;A61P29/00;C07D401/12;C07D401/14;C07D403/14;C07D405/14;C07D409/14;C07D417/12;C07D417/14	主分类号	C07D403/12
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