发明名称 |
Prostate specific antigen oligo-epitope peptide |
摘要 |
The invention is a prostate specific antigen oligo-epitope peptide which comprises more than one PSA epitope peptide, which conforms to one or more human HLA class I motifs. The prostate specific antigen oligo-epitope peptide in combination with various HLA-class I molecules or interactions with various T-cell receptors elicits PSA specific cellular immune responses. The prostate specific antigen oligo-epitope peptide is useful as an immunogen in the prevention or treatment of prostatic cancer, in the inhibition of prostatic cancer cells and in the establishment and characterization of PSA-specific cytotoxic T-cell lines.
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申请公布号 |
US2007098691(A1) |
申请公布日期 |
2007.05.03 |
申请号 |
US20060606929 |
申请日期 |
2006.12.01 |
申请人 |
THE GOVT. OF THE U.S.A., AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH & HUMAN SERVICES |
发明人 |
SCHLOM JEFFREY;TSANG KWONG-YOK;ZAREMBA SAM |
分类号 |
A61K48/00;A61K35/12;A61K38/00;A61K39/00;C07H21/04;C07K14/82;C12N5/06;C12N5/0783;C12N7/00;C12N9/64;C12N15/57;C12N15/86;C12Q1/68 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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