发明名称 FGFR1 EXTRACELLULAR DOMAIN COMBINATION THERAPIES
摘要 PROBLEM TO BE SOLVED: To provide combined anti-cancer therapeutic agents of drugs showing synergistic anti-tumor therapeutic activity, particularly therapeutic activity to non-small cell lung cancer.SOLUTION: An anti-cancer therapeutic agent comprises a combination of fibroblast growth factor receptor 1 (FGFR1) extracellular domain (ECD) and/or FGFR1 ECD fusion molecule with at least one additional therapeutic agent selected from paclitaxel, carboplatin, cisplatin, oxaliplatin, doxorubicin, 5-fluorouracil (5-FU), leucovorin, pemetrexed, etoposide, VEGF antagonist, VEGF trap, anti-VEGF antibody, or bevacizumab.SELECTED DRAWING: Figure 1
申请公布号 JP2016196475(A) 申请公布日期 2016.11.24
申请号 JP20160106022 申请日期 2016.05.27
申请人 FIVE PRIME THERAPEUTICS INC 发明人 LI LONG;THOMAS BRENNAN
分类号 A61K38/00;A61K31/37;A61K31/4745;A61K31/475;A61P11/00;A61P35/00 主分类号 A61K38/00
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