发明名称 |
COMPOSITIONS, METHODS, AND SYSTEMS FOR TISSUE FIXATION |
摘要 |
The present disclosure relates to use of high-concentration aldehyde-based fixatives to fix tissue samples. Aldehyde concentrations are selected that significantly increase rate of diffusion of the fixative solution into the tissue. When combined in the cold-temperature step of a two-temperature fixation, a substantial improvement in the preservation of post-translationally modified proteins is achieved. |
申请公布号 |
WO2016041890(A3) |
申请公布日期 |
2016.06.09 |
申请号 |
WO2015EP70927 |
申请日期 |
2015.09.14 |
申请人 |
VENTANA MEDICAL SYSTEMS, INC.;F. HOFFMANN-LA ROCHE AG |
发明人 |
CHAFIN, DAVID;OTTER, MICHAEL;THEISS, ABBEY;BAUER, DANIEL |
分类号 |
G01N1/30 |
主分类号 |
G01N1/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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