发明名称 METHODS FOR DETECTING AMYLOID BETA AMYLOIDOSIS
摘要 The present invention relates to methods of detecting, diagnosing, monitoring, and assessing treatment effects for Aβ amyloidosis, early in the course of clinical disease or prior to the onset of brain damage and clinical symptoms.
申请公布号 US2016178646(A1) 申请公布日期 2016.06.23
申请号 US201615057694 申请日期 2016.03.01
申请人 Washington University 发明人 Bateman Randall;Mawuenyega Kwasi;Ovod Vitaliy;Bareiss Anna;Kasten Tom;Holtzman David
分类号 G01N33/68;G01N33/58 主分类号 G01N33/68
代理机构 代理人
主权项 1. A method for detecting Aβ amyloidosis in a subject, the method comprising measuring the in vivo relative labeling of at least two Aβ variants in a blood sample from the subject, and calculating a ratio of relative labeling of the first Aβ variant to the relative labeling of the second Aβ variant, wherein a ratio other than 1 indicates the presence of Aβ amyloidosis.
地址 St. Louis MO US