| 主权项 |
1. A compound of formula I:or a pharmaceutically acceptable salt thereof,wherein:
each R1 is independently hydrogen, an optionally substituted C1-6 aliphatic group, an optionally substituted 3-7 membered monocyclic heterocyclic group, or an optionally substituted heterocyclylalkyl group having 3-7 carbon atoms and 1-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur;
or two R1 groups are taken together with their intervening atoms to form an optionally substituted 3-7 membered saturated or partially unsaturated monocyclic heterocyclic ring having 1-2 heteroatoms independently selected from nitrogen, oxygen, or sulfur; wherein optionally substituted groups may be substituted with halogen, —NO2, —CN, —OR, —SR, —N(R)2, —C(O)R, —CO2R, —N(R)C(O)OR, —C(O)N(R)2, —OC(O)R, —N(R)C(O)R, —S(O)R, —S(O)2R, or —S(O)2N(R)2; each R is independently hydrogen or C1-6 aliphatic;
or two R groups attached to the same nitrogen are taken together with their intervening atoms to form an optionally substituted 3-7 membered saturated or partially unsaturated monocyclic heterocyclic ring having 1-2 heteroatoms, in which any second heteroatom is independently selected from nitrogen, oxygen, or sulfur;Ring A isR2 is —Cl or —F; andR3 is —CF3, —OCF3, or —F. |
