发明名称 |
NOVEL P-SELECTIN LIGAND PROTEIN |
摘要 |
A novel P-selectin ligand glycoprotein in disclosed, characterized by the amino acid sequence set forth in SEQ ID NO:1 or by the amino acid sequence set forth in SEQ ID NO:3. DNA sequences encoding the P-selectin ligand protein are also disclosed, along with vectors, host cells, and methods of making the P-selectin ligand protein. Pharmaceutical compositions containing the P-selectin ligand protein and methods of treating inflammatory disease states characterized by P-selectin-mediated intercellular adhesion are also disclosed. |
申请公布号 |
WO9410309(A1) |
申请公布日期 |
1994.05.11 |
申请号 |
WO1993US10168 |
申请日期 |
1993.10.22 |
申请人 |
GENETICS INSTITUTE, INC. |
发明人 |
LARSEN, GLENN, R.;SAKO, DIANNE, S.;CHANG, XIAO-JIA;VELDMAN, GEERTRUIDA, M. |
分类号 |
C12N15/09;A61K31/711;A61K38/00;A61K38/17;A61K39/00;A61K39/395;A61K48/00;A61P1/02;A61P1/04;A61P3/10;A61P5/14;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P17/02;A61P19/02;A61P29/00;A61P31/04;A61P31/12;A61P35/04;A61P37/06;A61P37/08;A61P43/00;C07H21/04;C07K14/47;C07K14/705;C07K14/72;C07K16/28;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/00;C12N5/10;C12N9/10;C12N9/64;C12N15/12;C12N15/54;C12N15/57;C12P21/02;C12R1/91;G01N33/15;G01N33/50;G01N33/566 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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