ISOTOPE PREPARATION METHOD.

摘要

The present invention provides a method for the generation of ²²³Ra of pharmaceutically tolerable purity comprising i) preparing a generator mixture comprising ²²⁷Ac, ²²⁷Th and ²²³Ra; ii) loading said generator mixture onto a strong base anion exchange resin; iii) eluting said ²²³Ra from said strong base anion exchange resin using a first mineral acid in an alcoholic aqueous solution to give a first eluted ²²³Ra solution; iv) loading the ²²³Ra of the first eluted ²²³Ra solution onto a strong acid cation exchange resin; and v) eluting the ²²³Ra from said strong acid cation exchange resin using a second mineral acid in aqueous solution to provide a second eluted solution. The invention additionally provides products of corresponding purity and/or products obtained or obtainable by such a method.